3D Printed Catalytic Stirrer Devices
Traditional organic reactions often rely on the addition of catalysts to the reaction, which requires the time taken to weigh out the catalysts and at the end of the reaction, to remove these via purifiction, which all takes time. Our innovative approach focuses on the replacement of traditional stirrer devices with 3D printed ones that contain catalysts. In this way, the weighing out of catalysts are avoided and the device containing the catalyst is simply removed at the end of the reaction, greatly speeding up purification.
Lewis Acid Impregnated Stirrers
In this proeject we demonstrated that we can embed Lewis acids into our stirrer devices and that these can then be used to screen an array of reaction conditions and to quickly develop a library of compounds.
Optimising Mixing
The great thing about 3D printing is its ability to allow the user to modify the design to suit the application. Here you can see some advanced designs demonstrating how the stirrer devices can greatly increase mixing.
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Palladium Impregnated Catalysts
Whilst the incoporation of Lewis Acids is a great way to demonstate the power of our catalyst impreganted devices, the incorporation of palladium based catalysts is crucial for medicinal chemistry. In this paper, we demonstrated their potential to both speed up the reaction and that it proceeds cleaner and faster with embedded catalysts.
Speeding up a Reaction
The 3D Printed stirrer devices are ideal for speeding up a reaction and improving yield. Their improved mixing efficiency greatly improves both yield and reaction outcome as highlighted.
